The patent discloses a pharmaceutical composition comprising picroside isolated from Picrorrhize kurroa. The composition contains Picroside I as an active ingredient for treating drug-induced immunopathy such as neutropenia. Methods of isolating Picroside I and Picroside II, and preparing the compositions have also been disclosed herein. The said composition of Picroside I can be a solid oral or an injectable composition of a pre-determined dose. The said composition of Picroside I exhibited reversal of drug-induced immunopathy such as neutropenia through in vivo tests as well as in vitro tests. Therefore, it can be used as a herbal therapeutic agent for treating drug-induced immunopathy such as neutropenia.
| Patent Status: PCT application National Phase Entry completed in 11 countries Application under prosecution in CA, Israel, KR, US, AU, BR, Indonesia, CN and India. Patent granted in Russia, Japan and Europe Stage: Industrial stage The applicant is open for licensing or assignment |
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